Upregulation of COX-1 and COX-2 in nasal polyps in cystic fibrosis
نویسندگان
چکیده
منابع مشابه
Expression and localization of cyclooxigenases (Cox-1 and Cox-2) in nasal respiratory mucosa. Does Cox-2 play a key role in the immunology of nasal polyps?
INTRODUCTION Cyclooxygenases 1 (Cox-1) and 2 (Cox-2) play a key role in arachidonic acid metabolism and in the regulation of eicosanoid production. The balance of prostaglandin and leukotrien release in respiratory mucosa is a crucial factor in the development of Sampter's triad in NSAID (aspirin-) intolerant patients and possibly also relevant in the pathophysiology and immunology of chronic r...
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9 By the end of the training programme, the duration of a constant work rate treadmill task was increased by 79% in patients receiving bronchodilator treatment compared with those receiving placebo. Finally, in this issue of Thorax, Peters et al report that 50% oxygen breathing acts synergistically with bronchodilator therapy (ipratropium bromide) to reduce hyperinflation and improve exercise t...
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ژورنال
عنوان ژورنال: Thorax
سال: 2006
ISSN: 0040-6376
DOI: 10.1136/thx.2004.039842